RESEARCH: studies reviewed this month - April 2020

DETRAINING: Two Weeks of Reduced Activity Decreases Leg Lean Mass and Induces "Anabolic Resistance" of Myofibrillar Protein Synthesis in Healthy Elderly

During the period of quarantine in 2020 I was investigating the rate of detraining and the impact of reduced training load. This study looked at age-related muscle atrophy with the hypothesis that "during periods of muscle disuse, muscle protein synthesis is blunted, and muscle atrophy occurs in young and old". In particular the authors investigated "the impact of a short reduction in physical activity on muscle protein metabolism in older adults".

The methodology involved a 14-day period of reduced daily steps hoping to determine the impact on either a fasted and fed-state rate of myofibrillar protein synthesis (MPS). The results showed that:

Leg fat-free mass was reduced by approximately 3.9%. Postabsorptive insulin resistance was increased by approximately 12%, and postprandial insulin sensitivity was reduced by approximately 43% after step reduction. Postprandial rates of MPS were reduced by approximately 26% after the intervention, with no difference in postabsorptive rates.

14 days of reduced steps in older adults induces small but measurable reductions in muscle mass that appear to be underpinned by reductions in postprandial MPS and are accompanied by impairments in insulin sensitivity and systemic inflammatory markers and postprandial MPS.


PRACTICAL TAKE AWAY - as little as 14 days of reduced activity has an impact on older adults. Therefore it would be valuable to include some exercise and training even in a post-season break rather than having a period of complete rest.



NUTRITION: Effects of caffeine on neuromuscular function in a non‐fatigued state and during fatiguing exercise



HEAT: Wearing a Cap, Thermoregulation, and Thermal Sensation During Running in a Hot Environment



HEAT: Cooling the Neck Region During Exercise in the Heat



TRAINING: Physiological profile of adult male long-distance trail runners



SLEEP: Influence of a 30-Day Slow-Paced Breathing Intervention Compared to Social Media Use on Subjective Sleep Quality and Cardiac Vagal Activity



NUTRITION: Periodized Nutrition for Athletes



TRAINING: Multidisciplinary Analysis of Differences Between Finisher and Non-finisher Ultra-Endurance Mountain Athletes



NUTRITION: Effects of an Exogenous Ketone Supplement on Five-Kilometer Running Performance



HEAT: Humid heat acclimation does not elicit a preferential sweat redistribution toward the limbs



HEAT: Heat alleviation strategies for athletic performance: A review and practitioner guidelines



TRAINING: Physiological adaptations to interval training and the role of exercise intensity



TRAINING: Effects of 12 Weeks of Block Periodization on Performance and Performance Indices in Well-Trained Cyclists



NUTRITION: Fuel for the Work Required: A Theoretical Framework for Carbohydrate Periodization and the Glycogen Threshold Hypothesis



DETRAINING: One Week of Step Reduction Lowers Myofibrillar Protein Synthesis Rates in Young Men

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